Human Sera
Cayman Chemical 3hydroxy4Methoxyphenthyla 50mg
A metabolite of dopamine; decreases the viability of SH-SY5Y cells at 200 µM; induces tachycardia and increases blood pressure in normotensive or DOCA-salt hypertensive rats at 1 mg/kg; induces tremors and rigidity in mice at 100 mg/kg
Cayman Chemical Linolenoyl Ethanolamide 50mg
A member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids
Cayman Chemical Sulpho Nonate 50mg
Sulpho NONOate produces nitrous oxide but no NO at physiological pH. Therefore, this compound may be used as a negative control in experiments using other NO donors of the NONOate class.{875,5437}
Cayman Chemical 3FluoroethcathInonhydroch 50mg
A fluorine-substituted synthetic cathinone that has potential for abuse; intended for forensic and research applications
Cayman Chemical 4methylNMethylbuphedron 50mg
A para-methyl analog of buphedrone with an aminomethyl addition; intended for research and forensic applications
Cayman Chemical IonIzable LIpId 4 50mg
An ionizable cationic lipid (pKa = 6.1) and hydrogen peroxide-induced rearrangement product of the cationic lipid CA-lipid 5; CALNPs containing CA-lipid 5 and encapsulating siRNA against EGFP undergo hydrogen peroxide-induced removal of the phenylboronic acid groups from CA-lipid 5 in MCF-7 cells in vitro, generating ionizable lipid 4-containing LNPs with reduced positive charges at physiological pH, facilitating intracellular siRNA release and gene silencing; LNPs containing ionizable lipid 4 and encapsulating siRNA against PLK1 reduce tumor volume in an MCF-7 mouse xenograft model
Cayman Chemical DGlucosamIn6phosphatehy 100mg
A monosaccharide intermediate of the hexosamine biosynthetic pathway; binds the GlmS riboswitch (Ki = 380 µM) and inhibits GlmS production and decreases D-GlcN-6-P levels; precursor in the biosynthesis of UDP-GlcNAc
Cayman Chemical 15mthyl PalmItIc ACD mthy 50mg
A methylated fatty acid methyl ester; has been found in S. zeai sea sponges as the fatty acyl component of zeamide, oolong tea, and P. sulcate extract
Cayman Chemical NormetnphrInhydrochlorId 100mg
An active metabolite of norepinephrine; induces contractions in isolated rabbit aortic strips; inhibits norepinephrine uptake in isolated rat heart (IC50 = 200 µM); plasma levels of normetanephrine are increased in patients with von Hippel-Lindau disease and pheochromocytomas compared with patients with von Hippel-Lindau disease without pheochromocytomas; has been used as a marker of authentic human urine specimens
Cayman Chemical SertralInhydrochlorIde 50mg
A selective serotonin reuptake inhibitor; inhibits monoamine uptake by SERT (IC50 = 70 nM); selective for SERT over the norepinephrine and dopamine transporters (IC50s = 520 and 720 nM, respectively); reduces immobility in the forced swim test in mice at 3.2-56 mg/kg, s.c.; prevents acid sphingomyelinase activation and subsequent ceramide release induced by pp-VSV-SARS-CoV-2 infection in Vero cells at 5 µM
Cayman Chemical -GalocatechIn 100mg
A polyphenol and flavonoid that has diverse biological activities; inhibits adherence of P. gingivalis onto human buccal epithelial cells by >50% at 250 μg/ml; has antimutagenic properties in UV-irradiated E. coli cells; inhibits cell death induced by D-galactosamine and TNF-α in primary cultured mouse hepatocytes by 29.9% at 80 μM; inhibits HCT116 colorectal cancer cell proliferation by 57% at 100 μM